Assay
Age
|
Western blot
Postnatal
|
Mdm2 transformed mouse 3T3 cell double minute 2 (Synonyms: 1700007J15Rik, Mdm-2) | |
Results | Reference |
1 | J:317403 De Clercq S, Gembarska A, Denecker G, Maetens M, Naessens M, Haigh K, Haigh JJ, Marine JC, Widespread overexpression of epitope-tagged Mdm4 does not accelerate tumor formation in vivo. Mol Cell Biol. 2010 Nov;30(22):5394-405 |
1* | J:49215 Leveillard T, Gorry P, Niederreither K, Wasylyk B, MDM2 expression during mouse embryogenesis and the requirement of p53. Mech Dev. 1998 Jun;74(1-2):189-93 |
1 | J:329967 Li H, Li C, Zhai W, Zhang X, Li L, Wu B, Yu B, Zhang P, Li J, Cui CP, Zhang L, Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival. Cell Rep. 2022 Oct 4;41(1):111435 |
1 | J:123661 Terzian T, Wang Y, Van Pelt CS, Box NF, Travis EL, Lozano G, Haploinsufficiency of Mdm2 and Mdm4 in tumorigenesis and development. Mol Cell Biol. 2007 Aug;27(15):5479-85 |
1* | J:213978 Vuong L, Brobst DE, Saadi A, Ivanovic I, Al-Ubaidi MR, Pattern of expression of p53, its family members, and regulators during early ocular development and in the post-mitotic retina. Invest Ophthalmol Vis Sci. 2012 Jul;53(8):4821-31 |
1 | J:223276 Xiong X, Zhao Y, Tang F, Wei D, Thomas D, Wang X, Liu Y, Zheng P, Sun Y, Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis. Elife. 2014;3:e02236 |
1 | J:241249 Xue Y, Raharja A, Sim W, Wong ES, Rahmat SA, Lane DP, The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage. Oncogene. 2017 Apr 06;36(14):2002-2013 |
1 | J:339368 Yao F, Huang S, Liu J, Tan C, Xu M, Wang D, Huang M, Zhu Y, Huang X, He S, Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis. Cell Death Dis. 2023 Aug 23;14(8):543 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/30/2024 MGI 6.23 |
|
|